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Making MOFs, making connections, making scientists: Honors general chemistry series brings students into a community of innovation

By Malea Fulton, Honors College

This story was originally published by the Honors College.

From synthesizing metal-organic frameworks to presenting research findings, first-year students in the honors general chemistry sequence experience science as it is practiced in the real world. One of the longest-running honors offerings at Oregon State, the three-term series gives participating students access to advanced laboratory experiences, faculty mentorship and a learning community that often shapes their academic paths in their very first year.

The sequence, which teaches foundational chemistry concepts and skills to undergraduate students majoring in the sciences, has been offered as an honors course since the Honors College was founded in 1995. It was the college’s first full-year, multi-section course, initiated and originally taught by now-retired chemistry professor Jim Krueger. Krueger played a critical role in establishing the Honors College and was an early exemplar of the engaged and innovative teaching style that continues to characterize honors course instruction. He reflected in a 2019 interview that “teaching honors general chem was probably the best teaching experience of my career overall.”

This sentiment is echoed by Michael Burand, an associate professor of chemistry who oversees all 200-level general chemistry laboratory courses. Burand also taught the first-term lecture course for honors general chemistry in fall 2024 and 2025. “We all love teaching the honors lecture,” he said, speaking both for himself and his colleagues in the chemistry department. “I think we’d all teach it every term if we could.”

A man in a blue suit with a red bowtie poses for a photo.

Michael Burand, an associate professor of teaching in chemistry, directs the 200-level general chemistry laboratory program, including honors lab courses. He has served in this role since joining the OSU faculty in 2012.

What makes honors general chemistry a uniquely rewarding experience for students and instructors?

“A big part of it is the MOF lab,” says Karlie Bach, a chemistry Ph.D. student in May Nyman’s research group and head teaching assistant for general chemistry at Oregon State. Bach taught the honors lab section from 2022 to 2023 and has worked with Burand to develop unique chemistry lab projects for honors students to engage with every term. One of these projects — the MOF, or metal-organic frameworks lab — takes place in the spring and is a defining feature of honors general chemistry.

“The MOF lab gives honors students a really unique experience where they get to synthesize this compound (a MOF) and test it in a real-world application,” said Bach. “They synthesize and characterize it themselves. Then, they visit the OSU research team that focuses on metal-organic frameworks and see the instrumentation they use.”

One technique used to study MOFs is powder X-ray diffraction, and honors students get to observe this technique in action. “Having anything to do with powder X-ray diffraction in a general chemistry course … that Venn diagram doesn’t usually overlap,” Burand said. “So even seeing that equipment in use and analyzing the data it collects is infinitely more than the average general chemistry student in the United States gets to experience.”

Following MOF synthesis, students test their compound’s ability to remove harmful contaminants from solution, tying the teaching lab to the real world. The term culminates with a poster presentation where students present their MOF research to the chemistry department. “We talk with students about how to deliver an elevator speech of their research and how to field questions,” said Bach. “For students moving into their own honors theses, this full-circle scientific process — compound synthesis, testing, analysis and finally presentation — provides a valuable preview of the world of research and prepares them with skills in scientific inquiry and communication.”

The MOF lab often becomes a gateway for students to their future thesis work and mentor. “We’ve had a lot of undergrads who participate in that project and then reach out to Dr. Stylianou and ask to do research in his lab,” Bach said, with many completing theses under his mentorship.

Kyriakos Stylianou, an associate professor of chemistry, is “the faculty member who gets credit” for the MOF lab, said Burand. “When we incorporated this project into our honors general chemistry lab program in 2022, it was unique to OSU. To our knowledge, no other general chemistry program in the world was doing this project."

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